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Endeavor BioMedicines Reports Results from the P-IIa Study of ENV-101 for Treating Idiopathic Pulmonary Fibrosis

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Endeavor BioMedicines Reports Results from the P-IIa Study of ENV-101 for Treating Idiopathic Pulmonary Fibrosis

Shots:

  • The P-IIa study assesses the safety & efficacy of ENV-101 (200mg, QD) vs PBO to treat idiopathic pulmonary fibrosis patients (n=41) for 12wks.
  • The study showed a 1.9% vs 1.3% mean improvement in ppFVC, a 200mL increase in total lung capacity among 80% of patients vs 56mL decrease in 70% of them, reduced quantitative interstitial lung disease (QILD) by 9.4% vs 1.1% increase, quantitative lung fibrosis (QLF) by 2% vs 0.87% increase & quantitative ground glass (QGG) by 4.6% vs 0.29% increase
  • Based on presented data, the company to initiate P-II (WHISTLE-PF) study having a global P-IIb IPF arm & a parallel P-II progressive pulmonary fibrosis (PPF) arm, for which the company has secured $132.5M Series C funding

Ref: Aileron Therapeutics |Image: Aileron Therapeutics

Related News:- Aileron Therapeutics Reports Cohort 1 Results from the P-Ib Study of LTI-03 for Idiopathic Pulmonary Fibrosis (IPF)

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Disha Nankani

Disha is a content writer at PharmaShots. She is passionate and curious about recent updates and developments in MedTech and Pharma industry. She covers news related to clinical trial results and updates. She can be contacted at connect@pharmashots.com.

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